Fresh from a snub from Edinburgh on the proposal to play a match in Cape Town, Saracens have now had their New York plans dashed by NFL sides.
The Aviva Premiership outfit had hoped to take on Munster at the MetLife Stadium on December 15, but logistical problems have ended those hopes.
82,500 fans can fit in the stadium that is the home of the Giants and Jets, but the teams are unwilling to install rugby posts on the artificial pitch.
"We are in a unique position this season because our new stadium is not ready," Saracens chief executive Edward Griffiths told Sky Sports.
"I went to New York in July and looked at the MetLife Stadium. We looked at the size of the pitch and it came down in the end to the fact that we would need to put rugby posts into the artificial turf.
"The owners of the two NFL teams didn't want that.
"It was disappointing. My feeling was if we had been able to play there, we would have had a great occasion.
"The indication from Munster too was that they would be eager to receive a proposal.
"I think they had worked out that, for an Irish team to go to New York, it made quite a lot of sense."