Wales have made four changes to face Australia this Saturday in Cardiff, with Gethin Jenkins returning at loosehead prop.
The three other changes also come in the pack, with Aaron Shingler starting at blindside flanker, Scott Andrews in at tighthead prop for the injured Aaron Jarvis and Ian Evans replacing Bradley Davies in the second row.
The backline remains unchanged from last weekend's defeat to New Zealand, whilst on the bench Ryan Bevington, Samson Lee and Dan Biggar are all included along with Ryan Jones.
"We need to pick up again where we left off in the second half last week," said Wales head coach Warren Gatland.
"We managed to retain 73% possession after the break against the All Blacks and win the territory battle and we need to put Australia under similar pressure from the outset.
"We have played them regularly over the last couple of years and have come close to winning on a number of occasions, but have not quite been able to get ourselves over the chalk of the finish line.
"Both sides have had injuries to cope with, but there is every reason for optimism. The Millennium Stadium crowd will be in full voice again, they were outstanding last week, and we are aiming to reach the end of a tough series on Saturday and finish off on a high."
Wales: 15 Leigh Halfpenny, 14 Alex Cuthbert, 13 Jonathan Davies, 12 Jamie Roberts, 11 Liam Williams, 10 Rhys Priestland, 9 Mike Phillips, 8 Toby Faletau, 7 Sam Warburton (c), 6 Aaron Shingler, 5 Luke Charteris, 4 Ian Evans, 3 Scott Andrews, 2 Matthew Rees, 1 Gethin Jenkins.
Replacements: 16 Ken Owens, 17 Ryan Bevington, 18 Samson Lee, 19 Ryan Jones, 20 Justin Tipuric, 21 Tavis Knoyle, 22 Dan Biggar, 23 Scott Williams.
Date: Saturday, December 1
Kick-off: 14:30 GMT
Venue: Millennium Stadium
Referee: Wayne Barnes (England)
Assistant referees: Romain Poite (France), Greg Garner (England)
Television match official: Marshall Kilgore (Ireland)